For Epitope Mapping and Peptide Discovery
High-Density Peptide Microarrays
For Epitope Mapping and Peptide Discovery
Product Details
Elevate your research with our microarray's capability to screen up to 200,000 custom peptides simultaneously, dramatically enhancing throughput and accelerating the pace of discovery in a single experiment.
Incorporate proteinogenic and custom unnatural amino acids to unlock enhanced binder specificity, increased resistance to degradation, and improved pharmacokinetics.
Explore the realm of structural diversity with our peptide microarrays, designed to unlock the full potential of both linear and cyclic peptides and accelerate breakthroughs in drug discovery.
Products and Services
Combining bioinformatics with high-density peptide microarrays allows you to predict and validate linear, conformational, and discontinuous epitopes, in a single experiment.
Using AlphaFold models and proprietary algorithms, our Peptidome Chips display hundreds of thousands of unique peptides from entire proteomes, allowing detailed off-target activity analysis for safer drug development.
Design up to 200,000 custom peptides, including unnatural and cyclized variants, ideal for applications like epitope mapping and biomarker discovery, with expert guidance to ensure accurate and impactful results.
Our all-in-one Peptide Screening service, from microarray design to data analysis, provides rapid epitope identification and biomarker discovery, delivering results in just 21 days without the need for lab facilities.
Array Designs
Single-well layout is designed for exhaustive screenings and comprehensive experiments. It offers a single incubation well with the capacity to host up to 200,000 peptides per subarray. This layout is exceptionally suited for discontinuous epitope mapping and peptide discovery applications, where maximizing the peptide repertoire on a single substrate is crucial.
Designed for conducting dual analyses in parallel, the double-well option features 2 wells, each accommodating up to 79,000 peptides per subarray. This setup is ideal for experiments requiring simultaneous analysis of samples with control analytes, enabling direct comparison and validation of results within the same experimental run.
Catering to mid-size experiments, this layout presents 6 active wells, with each well capable of hosting up to 14,000 peptide spots. It allows for six different analyses per experiment, making it a versatile choice for studies that balance between high-throughput screening and detailed, targeted analysis across multiple samples or conditions.
Expanding the scope for broader analysis, the 12-well layout is equipped to manage studies involving multiple analytes, with each well supporting up to 4,800 peptides per subarray. This configuration is particularly suitable for linear epitope mapping, offering a balanced approach to dissecting complex antigen-antibody interactions across a wide array of samples.
With 18 subarrays, this layout is tailored for extensive linear epitope mapping, allowing up to 18 analytes to be analyzed in parallel. Each well can accommodate 3,200 peptides per subarray, making it adept at facilitating comprehensive screenings where a broad spectrum of potential epitopes across numerous analytes is under investigation.
The open chamber layout removes the constraints of well-defined subarrays, offering an unbounded canvas for the ultimate capacity experiments. This format is particularly effective for proteome-wide screenings, discontinuous epitope mapping, or peptide discovery applications that demand the freedom to utilize the entire array surface without the limitation of predefined sections. It supports up to 220,000 peptides, tailored to the scope of large-scale, ambitious scientific inquiries.
Technology
At axxelera, we combine digital photolithography with conventional solid-phase peptide chemistry to guide thousands of simultaneous chemical reactions with unprecedented spatial resolution.
At axxelera, we combine digital photolithography with conventional solid-phase peptide chemistry to guide thousands of simultaneous chemical reactions with unprecedented spatial resolution.
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